Azithromycin and severe asthma

Azithromycin-induced severe Thrombocytopenia: A rare entity

Drug-induced thrombocytopenia (DITP) is a well-established but underdiagnosed condition. The condition is mostly asymptomatic, but can also cause severe bleeding [1]. Thrombocytopenia is a wellknown side effect of treatment with several types of medications. Therapeutic agents, speci ically those used for chemotherapy and immunosuppressants, tend to repress hematopoiesis and generate pancytopen...

[Severe asthma].

Is it severe asthma or asthma with severe comorbidities?

Severe asthma is defined as asthma that requires treatment with high-dose inhaled corticosteroids (ICSs) plus a second controller and/or systemic corticosteroids to prevent it from becoming uncontrolled or that remains uncontrolled despite this therapy. This definition has limitations: 1) it does not define any biological characteristic that distinguishes severe asthma from asthma in general an...

Benefits of omalizumab on anxiety and depression in patients with severe asthma

Background: Asthma is one of the most common chronic diseases and may cause psychiatric disorders affecting the patients’ quality of life. In our study, we evaluated the effect of omalizumab treatment on anxiety disorder and depression using Beck Depression Scale (BDS) and State Trait Anxiety Inventory (STAI). Methods: Anxiety level was determined with STAI, whereas depression level was ...

Clinical review: Severe asthma

Severe asthma, although difficult to define, includes all cases of difficult/therapy-resistant disease of all age groups and bears the largest part of morbidity and mortality from asthma. Acute, severe asthma, status asthmaticus, is the more or less rapid but severe asthmatic exacerbation that may not respond to the usual medical treatment. The narrowing of airways causes ventilation perfusion ...